A20201
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
Product description

presenilin 1(PSEN1) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result

Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Mouse,Rat
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Presenilin 1 (S357) Polyclonal Antibody detects endogenous levels of Presenilin 1 protein only when phosphorylated at S357.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357. AA range:323-372
Uniprot No
P49768
Alternative names
PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
presenilin 1(PSEN1) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result
Other
Gene_name: PSEN1 ; Protein_name: Presenilin-1; Expression: Blood,Brain,Epithelium,Human lung,Megakaryocyte,Platelet,Skin,
Mol.Wt (Da)
43 kD
Concentration
1 mg/ml