

Product description
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3
Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Mouse,Rat
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-PDK1 (S241) Polyclonal Antibody detects endogenous levels of PDK1 protein only when phosphorylated at S241.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human PDK1 around the phosphorylation site of Ser241. AA range:210-259
Uniprot No
O15530
Alternative names
PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3
Other
Gene_name: PDPK1 ; Protein_name: 3-phosphoinositide-dependent protein kinase 1; Expression: Brain,Coronary artery,Embryonic kidney,Epithelium,Kidney,My
Mol.Wt (Da)
63 kD
Concentration
1 mg/ml
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