A18380
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
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Product description

nibrin(NBN) Homo sapiens Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition.

Source
Rabbit
Applications
WB,IF,ELISA
Reactivity
Human
Dilution
WB: 1/500 - 1/2000. IF: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Nibrin (S278) Polyclonal Antibody detects endogenous levels of Nibrin protein only when phosphorylated at S278.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Nibrin around the phosphorylation site of Ser278. AA range:251-300
Uniprot No
O60934
Alternative names
NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
nibrin(NBN) Homo sapiens Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition.
Other
Gene_name: NBN ; Protein_name: Nibrin; Expression: Brain,Colon endothelium,Epithelium,Fibroblast,Skin,Synovial cell,
Mol.Wt (Da)
85 kD
Concentration
1 mg/ml

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