

Product description
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway
Source
Rabbit
Applications
IHC,ELISA
Reactivity
Human,Mouse
Dilution
IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-MLK1/2 (T312/266) Polyclonal Antibody detects endogenous levels of MLK1/2 protein only when phosphorylated at T312/266.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human MLK1/2 around the phosphorylation site of Thr312/266. AA range:281-330
Uniprot No
P80192/Q02779
Alternative names
MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway
Other
Gene_name: MAP3K9/MAP3K10 ; Protein_name: Mitogen-activated protein kinase kinase kinase 9/10; Expression: Colon epithelium,Spleen,
Mol.Wt (Da)
kD
Concentration
1 mg/ml
-
Promotion
-
Order
-
Online message
-
Help center