

Product description
domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation
Source
Rabbit
Applications
WB,IHC,IF,ELISA
Reactivity
Human,Mouse
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. IF: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human KSR2. AA range:671-720
Uniprot No
Q6VAB6
Alternative names
KSR2; Kinase suppressor of Ras 2; hKSR2
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation
Other
Gene_name: KSR2 ; Protein_name: Kinase suppressor of Ras 2; Expression: Testis,
Mol.Wt (Da)
108 kD
Concentration
1 mg/ml
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