

Product description
huntingtin(HTT) Homo sapiens Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the hun
Source
Rabbit
Applications
IHC,ELISA
Reactivity
Human,Mouse,Rat
Dilution
IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-Huntingtin (S421) Polyclonal Antibody detects endogenous levels of Huntingtin protein only when phosphorylated at S421.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Huntingtin around the phosphorylation site of Ser421. AA range:387-436
Uniprot No
P42858
Alternative names
HTT; HD; IT15; Huntingtin; Huntington disease protein; HD protein
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
huntingtin(HTT) Homo sapiens Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the hun
Other
Gene_name: HTT ; Protein_name: Huntingtin; Expression: Brain,Caudate nucleus,Frontal cortex,Muscle,Platelet,Retina,
Mol.Wt (Da)
348 kD
Concentration
1 mg/ml
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