A15555
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
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Product description

function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD

Source
Rabbit
Applications
WB,ELISA
Reactivity
Human
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Storage
-20°C/1 year
Specificity
HECW1 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized peptide derived from part region of human protein
Uniprot No
Q76N89
Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD
Other
Gene_name: HECW1 KIAA0322 NEDL1 ; Protein_name: E3 ubiquitin-protein ligase HECW1 (EC 6.3.2.-) (HECT, C2 and WW domain-containing protein 1) (NEDD4-like E3 ubiquitin-protein ligase 1) (hNEDL1); Expression: Brain,
Mol.Wt (Da)
176 kD
Concentration
1 mg/ml

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