A14776
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
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Product description

function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues up

Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Mouse,Monkey
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-FRS2 (Y436) Polyclonal Antibody detects endogenous levels of FRS2 protein only when phosphorylated at Y436.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436. AA range:402-451
Uniprot No
Q8WU20
Alternative names
FRS2; Fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues up
Other
Gene_name: FRS2 ; Protein_name: Fibroblast growth factor receptor substrate 2; Expression: Hippocampus,Placenta,Uterus,
Mol.Wt (Da)
65 kD
Concentration
1 mg/ml

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