A13994
Size
  • 50ul
  • 100ul
Price
  • $129
  • $229
Qty
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Product description

function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity

Source
Rabbit
Applications
WB,IHC,IF,ELISA
Reactivity
Human,Mouse
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. IF: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-eIF4B (S422) Polyclonal Antibody detects endogenous levels of eIF4B protein only when phosphorylated at S422.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437
Uniprot No
P23588
Alternative names
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity
Other
Gene_name: EIF4B ; Protein_name: Eukaryotic translation initiation factor 4B; Expression: Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung
Mol.Wt (Da)
80 kD
Concentration
1 mg/ml

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