

Product description
function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in
Source
Rabbit
Applications
WB,ELISA
Reactivity
Human,Mouse
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Storage
-20°C/1 year
Specificity
EDEM1 Polyclonal Antibody detects endogenous levels of protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Synthesized peptide derived from part region of human protein
Uniprot No
Q92611
Form
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in
Other
Gene_name: EDEM1 EDEM KIAA0212 ; Protein_name: ER degradation-enhancing alpha-mannosidase-like 1; Expression: Bone marrow,Primary B-Cells,Skin,
Mol.Wt (Da)
72 kD
Concentration
1 mg/ml
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