

Product description
function:Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to c
Source
Rabbit
Applications
WB,IHC,IF,ELISA
Reactivity
Human,Mouse
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. IF: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
CUL-2 Polyclonal Antibody detects endogenous levels of CUL-2 protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Cullin 2. AA range:696-745
Uniprot No
Q13617
Alternative names
CUL2; Cullin-2; CUL-2
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to c
Other
Gene_name: CUL2 ; Protein_name: Cullin-2; Expression: Brain,Kidney,Skin,
Mol.Wt (Da)
87 kD
Concentration
1 mg/ml
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