

Product description
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of
Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Mouse,Rat
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Csk Polyclonal Antibody detects endogenous levels of Csk protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human CSK. AA range:330-379
Uniprot No
P41240
Alternative names
CSK; Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of
Other
Gene_name: CSK ; Protein_name: Tyrosine-protein kinase CSK; Expression: Brain,Lung,Spleen,Uterus,
Mol.Wt (Da)
50 kD
Concentration
1 mg/ml
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