

Product description
function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is requir
Source
Rabbit
Applications
IHC,ELISA
Reactivity
Human
Dilution
IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
53BP1 Polyclonal Antibody detects endogenous levels of 53BP1 protein.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human TP53BP1. AA range:1744-1793
Uniprot No
Q12888
Alternative names
TP53BP1; Tumor suppressor p53-binding protein 1; 53BP1; p53-binding protein 1; p53BP1
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is requir
Other
Gene_name: TP53BP1 ; Protein_name: Tumor suppressor p53-binding protein 1; Expression: Cerebellum,Cervix,Epithelium,Myeloid leukemia cell,Skeletal muscle,
Mol.Wt (Da)
213 kD
Concentration
1 mg/ml
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