

Product description
function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is requir
Source
Rabbit
Applications
WB,IHC,ELISA
Reactivity
Human,Mouse,Rat,Monkey
Dilution
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage
-20°C/1 year
Specificity
Phospho-53BP1 (S6) Polyclonal Antibody detects endogenous levels of 53BP1 protein only when phosphorylated at S6.
Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human 53BP1 around the phosphorylation site of Ser6. AA range:1-50
Uniprot No
Q12888
Alternative names
TP53BP1; Tumor suppressor p53-binding protein 1; 53BP1; p53-binding protein 1; p53BP1
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Background
function:May have a role in checkpoint signaling during mitosis (By similarity). Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.,PTM:Asymmetrically dimethylated on Arg residues by PRMT1. Methylation is requir
Other
Gene_name: TP53BP1 ; Protein_name: Tumor suppressor p53-binding protein 1; Expression: Cerebellum,Cervix,Epithelium,Myeloid leukemia cell,Skeletal muscle,
Mol.Wt (Da)
213 kD
Concentration
1 mg/ml
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